Cannabinoids Can Treat & Prevent Osteoporosis
Osteoporosis is a term that describes the porous nature of bones. It is linked to the aging process. It is a disorder characterized by loss of bone mass and the mineral content of bones, making it susceptible to fractures. Some studies have been done on the therapeutic effects of industrial hemp-derived cannabinoids on the treatment of osteoarthritis and results show that it helps reduce the risk of osteoporosis while strengthening bone tissue.
First, What is Osteoporosis?
Osteoporosis is a disorder characterized by reduced bone density, reducing the strength of bones and ultimately resulting in fragile bones. This disorder causes bones to become compressible and porous. It is a disorder that affects the skeletal system, causing the bones to weaken, and then resulting in frequent fractures and bone breaks.
Before osteoporosis sets in fully, the patient will first experience what is known as osteopenia. This is a bone disorder where the density of the bone reduces and is not as dense as a healthy bone, though it isn’t close to the point of bone in osteoporosis.
The normal bone is made up of protein, calcium, and collagen. All these contribute to the strength of the bone. Bones that are affected by osteoporosis can break or have a fracture with a very minor injury that normally wouldn’t cause a fracture.
The break or fracture may occur in a crack form, such as in a fractured hip, or in a collapsing form, like a vertebral or compression fracture. The spine, wrists, ribs, and hips are all susceptible to fractures, but osteoporosis-related fractures may also occur in any skeletal bone.
How Industrial Hemp Can be an Effective Treatment for Osteoporosis
According to recent studies, the cannabinoids cannabidiol (CBD), tetrahydrocannabinol (THC) and cannabigerol (CBG) accelerate the healing of bones, slow the degeneration of bone and aid in disease prevention. Industrial hemp-derived cannabinoids and osteoarthritis treatment help to control arthritis pain and osteoporosis.
The endocannabinoid system (ECS) regulates the interaction between the mind and the body through cannabinoids and cannabinoid receptors (CB1 and CB2). It plays a vital role in growing, strengthening, and preserving the bones. The ECS affects the nervous system, organ function, and even the immune system. It works to maintain homeostasis, a term which describes the state of balance of the internal environment. Because the CB1 and CB2 receptors interact with other biochemical networks in the body, such as the immune system, they become active against bone ailments.
During one study, animals were injected with CBD. The CBD was injected into broken thigh bones. The same was done with THC. While THC did not show much healing effects, CBD did. The researchers observed that though the CBD-treated animals did not heal quicker, the previous fracture, due to the strengthened fracture callus, became less likely to encounter a future break. According to the study, the strength of the treated bone was up to 50% stronger than untreated bone.
Symptoms of Osteoporosis That Can Be Treated by Industrial Hemp
While cannabinoids have a positive effect on recovery of bone injury and prevention of osteoporosis and other bone diseases, industrial hemp-derived cannabinoids can also be an effective pain management mechanism. Other ways that industrial hemp can help include:
- Chronic post-injury pain
- Fracture pain
The Importance of Educating About Cannabinoids Now
The demographic that could benefit from using cannabinoids to treat and prevent osteoporosis needs education about and access to the effects of cannabinoids. Now that legislators and physicians are championing cannabinoid use along with advocates, there is a greater opportunity to remove the stigma and encourage patients to learn about the science behind the way this natural medicine works, rather that the old, worn-out myths from nearly a century ago.
They deserve to know that industrial hemp-derived cannabinoids are legal, non-lethal, non-psychoactive due to their less than .3% THC content and that they have a wealth of benefits that work with the body’s natural ECS. They need to be guided toward high-quality, tested products. Whether to treat a condition or prevent diseases or aches and pains, our aging population’s quality of life could be greatly increased by cannabinoids. It’s time to support researchers for further study and for those who can speak with authority about cannabinoids to do so.
- Bab, I.A. (2007, November). Regulation of skeletal remodeling by the endocannabinoid system. Annals of the New York Academy of Sciences, 1116, 414-22. Retrieved from http://onlinelibrary.wiley.com/wol1/doi/10.1196/annals.1402.014/full.
- Bab, I., & Zimmer, A. (2008). Cannabinoid receptors and the regulation of bone mass. British Journal of Pharmacology, 153(2), 182–188. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219540/.
- Bab, I., Zimmer, A., and Melamed, E. (2009). Cannabinoids and the skeleton: from marijuana to reversal of bone loss. Annals of Medicine. 41(8), 560-7. Retrieved from http://www.tandfonline.com/doi/full/10.1080/07853890903121025?needAccess=true.
- Idris, A. I., van ‘t Hof, R. J., Greig, I. R., Ridge, S. A., Baker, D., Ross, R. A., & Ralston, S. H. (2005). Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors. Nature Medicine, 11(7), 774–779. Retrieved from https://www.nature.com/nm/journal/v11/n7/full/nm1255.html.
- Idris, A. I. (2010). Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies. Current Neuropharmacology, 8(3), 243–253. Retrieved from http://www.eurekaselect.com/72288/article.
- Idris, A.I., and Ralston, S.H. (2010, October). Cannabinoids and bone: friend or foe? Calcified Tissue International, 87(4), 285-87. Retrieved from https://link.springer.com/article/10.1007%2Fs00223-010-9378-8.
- Idris, A.I., Sophocleous, A., Landao-Bassonga, E., Canals, M., Milligan, G., Baker, D., van’t Hof, R.J., and Ralston, S.H. (2009, August). Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells. Cell Metabolism, 10(2), 139-47. Retrieved from http://www.cell.com/cell-metabolism/fulltext/S1550-4131(09)00202-2?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413109002022%3Fshowall%3Dtrue.