An Unexplored Cannabinoid | CBGM

An Unexplored Cannabinoid | CBGM

What Is CBGM?

Cannabigerol Monomethyl Ether (CBGM) is a natural cannabinoid of the cannabigerol (CBG) group. Cannabinoids in the CBG group are placed together because they possess similar properties – properties that are almost the same as CBG. Like many other cannabinoids, we do not know much about CBGM.

Cannabis plants in North-East Asia seem to have the highest concentration of CBGM. In a particular study featuring cannabis plants grown in Sweden, it was discovered that seeds originating from South Africa have elevated levels of CBGM. However, whether this result was impacted by cross-pollination or was organic is not known.

CBGM was discovered in 1968 by researchers from the Kyushu University in Japan. The discovery was made after the compound was isolated from the Minamioshihara No. 1, a Japanese strain of hemp. It is one of only two ether cannabinoid compounds with an oxygen atom bonded to two alkyl groups or two aryl groups.

What Are the Therapeutic Benefits of CGBM?

Beyond the molecular structure, no clear difference has been identified between the CBGM and other cannabinoids in the CBG group. It is possible that this compound may have similar effects on the human body as other cannabinoids. Due to the fact that CBGM is an ether compound, it may impact the body in ways that are unique and completely different than those of other cannabinoids. To glean some comprehensive knowledge of how CBGM may compare to CBG, similar strains are observed by scientists.

Cannabidiol (CBD) has a non-psychoactive counterpart known as cannabidivarin (CBDV). Both share a similar structure. They provide relief without giving the user any psychoactive effects, such as those given by tetrahydrocannabinol (THC). On the other hand, THC has tetrahydrocannabivarin (THCV) as its counterpart. THCV can oppose or neutralize the effects of THC, suppressing an individual’s appetite, rather than enhancing the hunger feeling. Even though we have given only two examples, it is an indication that similar cannabis compounds may have entirely different or entirely similar therapeutic benefits.

To understand the full therapeutic potential of CBGM, it is imperative that additional research be conducted. Presently, the therapeutic benefits of CBGM to the following medical conditions are a mere speculation. If CBGM does mimic CBG without any side effects, then it may help checkmate the following conditions:

  • Severe nausea
  • Glaucoma
  • Chronic pain
  • Crohn’s disease
  • Cancer
  • Arthritis
  • Psoriasis.

If you wish to learn more about the therapeutic benefits of CBGM and other cannabinoids in that group, it’s best to consult a knowledgeable or licensed cannabis-trained physician.

Does It Have Any Side Effects?

There may be some side effects linked to the usage of CBGM. Of course, this is a common feature when one ingests artificial or natural substances. Though a lot of studies have confirmed that there is no harm in using cannabis compounds for the short term, there are also speculations that an individual may become addicted to some of the compounds via prolonged usage. Studies show that the individual may develop some form of dependency. However, these claims are mere speculation as no concise research has been carried out to verify it. Some studies also suggest that some cannabinoids may be used for the treatment of addiction to other substances.

Though we do not have adequate information on the short- and long-term effects of CBGM on the human body, users are advised to consult their physician or marijuana doctor prior to usage.

References

Elsohly, M. A; Radwan, M. M; Gul, W; Chandra, S; Galal, A (2017). “Phytochemistry of Cannabis sativa L”. Progress in the Chemistry of Organic Natural Products. Progress in the Chemistry of Organic Natural Products. 103: 1–36.

Turner, S. E; Williams, C. M; Iversen, L; Whalley, B. J (2017). “Phytocannabinoids”. Progress in the Chemistry of Organic Natural Products. 103: 61–101.

Morales, P; Reggio, P. H; Jagerovic, N (2017). “An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol”. Frontiers in Pharmacology. 8: 422.

Morales, P; Hurst, D. P; Reggio, P. H (2017). “Molecular Targets of the Phytocannabinoids – A Complex Picture”. Progress in the chemistry of organic natural products. Progress in the Chemistry of Organic Natural Products. 103: 103–131.   

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